Bei Chen Selected Research

Lung Neoplasms (Lung Cancer)

1/2016	Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers.
3/2013	Expression of NDRG2 in human lung cancer and its correlation with prognosis.

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Bei Chen Research Topics

Disease

24	Neoplasms (Cancer) 11/2022 - 11/2003
12	Rhinosinusitis 01/2017 - 05/2007
8	Inflammation (Inflammations) 05/2022 - 05/2006
8	Stomach Neoplasms (Stomach Cancer) 03/2017 - 04/2008
6	Infections 07/2022 - 05/2006
5	Nasal Polyps (Nasal Polyp) 01/2018 - 01/2008
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2016 - 03/2013
4	Echinococcosis (Hydatid Cysts) 07/2021 - 01/2020
4	Bacterial Infections (Bacterial Infection) 02/2021 - 03/2014
4	Neoplasm Metastasis (Metastasis) 01/2014 - 02/2009
3	Circulating Neoplastic Cells 03/2022 - 04/2019
3	Pneumonia (Pneumonitis) 06/2021 - 07/2002
3	Human Influenza (Influenza) 06/2021 - 09/2011
3	Hearing Loss (Hearing Impairment) 01/2021 - 01/2020
3	Septic Shock (Toxic Shock Syndrome) 11/2011 - 01/2008
2	Wounds and Injuries (Trauma) 08/2022 - 07/2013
2	COVID-19 07/2022 - 03/2022
2	Diabetic Nephropathies (Diabetic Nephropathy) 05/2022 - 01/2022
2	Hyperglycemia 01/2022 - 03/2014
2	Viral Pneumonia 06/2021 - 02/2021
2	Virus Diseases (Viral Diseases) 06/2021 - 09/2011
2	Cysts 06/2020 - 01/2020
2	Melanoma (Melanoma, Malignant) 01/2019 - 03/2017
2	Polyps 01/2018 - 01/2008
2	Postoperative Pain 01/2018 - 01/2016
2	Pain (Aches) 01/2018 - 01/2017
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2017 - 01/2017
2	Lung Neoplasms (Lung Cancer) 01/2016 - 03/2013
2	Esophageal Squamous Cell Carcinoma 11/2014 - 01/2014
2	Respiratory Tract Diseases (Respiratory Tract Disease) 05/2014 - 03/2014
2	Allergic Rhinitis 03/2014 - 12/2013
2	Adenocarcinoma of Lung 01/2014 - 03/2013
2	Presbycusis 08/2011 - 07/2010
2	Squamous Cell Carcinoma of Head and Neck 03/2004 - 11/2003
1	Esophageal Neoplasms (Esophageal Cancer) 11/2022
1	Cicatrix (Scar) 08/2022
1	Fatigue 07/2022
1	Cough 07/2022
1	Skin Diseases (Skin Disease) 05/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Hyperlipidemias (Hyperlipidemia) 01/2022
1	Alcoholic Hepatitis 01/2022

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 05/2022 - 11/2003
7	Pharmaceutical PreparationsIBA 07/2021 - 04/2008
6	DNA (Deoxyribonucleic Acid)IBA 05/2022 - 03/2004
4	Peptides (Polypeptides)IBA 01/2022 - 10/2008
4	ImmunosorbentsIBA 11/2011 - 01/2008
4	EnzymesIBA 11/2011 - 01/2008
3	CytokinesIBA 05/2022 - 06/2014
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 03/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 10/2019
3	Anti-Bacterial Agents (Antibiotics)IBA 02/2021 - 11/2009
3	Biological ProductsIBA 01/2021 - 06/2014
3	Messenger RNA (mRNA)IBA 07/2020 - 03/2013
3	SuperantigensIBA 11/2011 - 01/2008
3	ExotoxinsIBA 11/2011 - 01/2008
2	Therapeutic UsesIBA 07/2022 - 09/2009
2	HydrogelsIBA 03/2022 - 04/2021
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2022 - 01/2018
2	Photosensitizing Agents (Photosensitizers)IBA 01/2022 - 03/2013
2	Phospholipases (Phospholipase)IBA 06/2021 - 02/2021
2	Albendazole (Albenza)FDA Link 06/2020 - 03/2020
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 08/2012
2	Folic Acid (Vitamin M)FDA LinkGeneric 07/2019 - 03/2018
2	Circular RNAIBA 01/2019 - 10/2017
2	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 06/2014
2	Interleukin-15 (Interleukin 15)IBA 03/2017 - 06/2014
2	FlavonesIBA 01/2017 - 01/2017
2	LipopolysaccharidesIBA 12/2016 - 07/2002
2	LigandsIBA 02/2016 - 06/2014
2	Antimicrobial PeptidesIBA 01/2016 - 03/2014
2	ErbB Receptors (EGF Receptor)IBA 12/2015 - 01/2014
2	Tyrosine Kinase InhibitorsIBA 12/2015 - 01/2014
2	Activating Transcription Factor 4IBA 11/2014 - 01/2014
2	Gefitinib (Iressa)FDA Link 01/2014 - 08/2013
2	Biomarkers (Surrogate Marker)IBA 01/2014 - 01/2012
2	Galactose (Galactopyranose)FDA LinkGeneric 08/2011 - 07/2010
2	Small Interfering RNA (siRNA)IBA 06/2010 - 06/2009
1	1,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA 11/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2022
1	CollagenIBA 08/2022
1	AutoantibodiesIBA 07/2022
1	weishuIBA 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	candesartanIBA 01/2022
1	TabletsIBA 01/2022
1	Simvastatin (Zocor)FDA LinkGeneric 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2022

Therapy/Procedure

14	Therapeutics 01/2022 - 10/2008
4	Acupuncture Points (Acupuncture Point) 07/2022 - 01/2022
4	Drug Therapy (Chemotherapy) 06/2020 - 04/2008
3	Electroacupuncture 05/2022 - 01/2018
3	Immunotherapy 01/2022 - 03/2017
2	Aftercare (After-Treatment) 11/2022 - 01/2018
2	Percutaneous Collagen Induction 07/2022 - 01/2018
2	Oral Administration 06/2021 - 01/2020
2	Radiotherapy 10/2008 - 03/2004
1	Subcutaneous Injections 01/2022
1	Microspheres (Microsphere) 01/2022